Can anyone help me choose the best preset for shooting in High Def 60i?

I'm looking for rich skin tones. It's video, so I like it to be sharp and heightened, without being overblown. Shooting people.

I tried CP 17, from that download, and it seems to be pretty good.

Also, when you use presets, is it still good to do a manual white balance, or should i leave it on Auto white balance?

I always do a manual white balance when the lighting will be consistent. Preset or no preset. You will get the best quality when you have static lighting with manual white balance.

Search the preset forum for Steven Dempseys CP30. It's the famed VIVIDRGB.
Great for your needs. The favourite of many here.

Trev

#16 EOSPHOTO might work well for your purposes, I've been pleased with the results using it.